I've messed around with a bunch of combos and so far I like the best (on an Eagle):
2x Wyrm II, 2x PROMETHEUS, 2x SILVER FIRE
All 3.03 guns, the proj speed on the Wyrms is 700 vs. 600 on the rest but it doesn't seem to matter much. Oh, and the projectile graphics on all 3 guns look cool

Maybe it's an old skool thing, my roots are firmly planted in Wing Commander where the endgame ships tended towards big heavy gun loadouts. That, and we didn't have any target tracking reticles, at least not for the first 2 games. We didn't need no stinking reticles anyway. We learned how to aim

Ever get the feeling... you're standing on plastic?