Cardamine from Buffalo to Manhatten. If your in a Rhino it's a $20,000+ profit run and then fly H-Fuel back to Buffalo, should be good for about $2-5k profit. The cardamine run is the honey pot, but you have to avoid the cops and the navy.
The best way to do it is drop out of the trade lane about 15 k before West point, fly around West Point and back into the manhatten trade lane. Drop out of the trade lane 15 k short of Manhatten, then fly to the eastern edge of manhatten and skim the edge of the atmosphere using cruise engines and quickly dock as soon as your 500m of the docking ring. You shouldn't get scanned at all that way, though you may be unlucky a few times.
Also you have to be at least neutral with the Rogues before you can land at thier base.
I don't really run this place but I have an understanding with the people who do.