You have the routes, you have the cargo type, you have the profit per tonne (sell-buy) & you have the ship.

Do the runs, write down the time taken, do the maths and let us know... :p

Smith & Wesson: the original point-and-click device[!

there's a thread explaning this in this forum somewhere

There are several...

If I had a nickel for every time someone told me that my idea for melting down coins to make a giant robotic parrot was a bad idea, I would have one kicka$$ giant robotic parrot.

Cant find them.... Anyway, i cant play Freelancer very often so i just try to ask you guys

Well, I stole this from someone on the forum. sadly, I can't remember that persons name.
Sorry.
He/she said that it's the best Single-Player trade route

Planet New Berlin, New Berlin System
Purchase Engine Components - 225. Take Jumphole to Sigma 13. Go to Yanagi Depot to sell your Engine Components for 524

Yanigi Depot, Sigma 13 system.
Purchase cardamine - 510. Go back to New Berlin, sell Cardamine for 1,349
Total profit per unit round 1,138
The whole trip only takes about 4-5 min..!

*NOTE* Yanagi Depot is controlled by Junkers...
Sorry I can't remember who's tip is is.
Fell free to take the credit

*Sigh* I Just said: WITHOUT THE SIGMA 13 JUMP HOLE TO NEW BERLIN...

I know damn well of that run, but its just not as profitable if you go through frankfurt.... The sigma 13 jump hole is closed in MP

planet malta, omicron alpha <-> rochester base, new york system

buy in malta (outcast) cardamine (drug, u may not have have this in ur cargo)
and i know, u can sell them better in manhattan....

sell the in rochester base (junkers), sell there the cardamine and buy there light arms, the light arms u take back to planet malta

cardamine - malta $300
rochester base somewhere in the $1400
manhattan $1500

light arms - manhattan - not buyable here
rochester base $100 a $200 if i'm right
malta $1400

I do mostly no cargo if i go from base to base, i'm more a criminal and a pirate, so destroy transporters with a good type of cargo

i traded between thus bases not enymore, it will take 15 minits to get from malta to rochester , if they don't attack u.

do some good missions at malta, and u make faster money

i never had a freighter, i like hunting down others better

With a Humpback (250 units):

Artifacts at Crete in Omicron Gamma to New Berlin=212,000 profit, Light Arms from The Ring back to Crete=262,500 profit (475K profit round trip). I don't know how long it takes, but it's only about 4 or 5 jumpholes/jumpgates either way.

If you're carrying Light Arms you can use tradelanes in New Berlin and Stuttgart, then jumpholes in Omega 11 and Omega 41. With Artifacts use jumpholes, go through Dresden instead of Stuttgart, and come in below Planet New Berlin. I've never gotten scanned until after I drop off my cargo in New Berlin.

For this route you have to friendly or neutral with the Corsairs, and it's nearly impossible without being friendly or neutral with the Red Hessians. And after you make a run or two you trade in the Humpback at Crete for a Titan.