At this moment my pilot is the most wanted pilot in Sirius. All government houses, Police houses, BountyHunters and trading compagnies seriously hate my gutts. All criminal factions ADORE me
A fully equipped Sabre mounted with 2 Nomad blasters, 2 Nomad Canons and 2 Kraken type 2 weapons and a Adv Brigadine lvl10 shield is capable is fencing off almost everyone. There is only one opponent that makes me pull everything out of my Sabre and those are the GMG. With their Sunblasts/Skyblast weapons they are doing lots of damage in a very short time. (Sky/Sunblast has a ref rate of 8.33 O.o)
So yeah, going trough "civilised" space is a pain, but not a real pain. Most of their weapons don't harm me much. Of course I don't just "hang" around in space. I kill for cash, no matter who I need to kill. (No PK tho, only NPC's) When I'm using a tradelane and it's hacked, I kill the ones that hack my tradelane and they still love me
The only problem you will have in the beginning is that you don't really know where all the criminal' bases are. So the exploring is a big part. Also, I really loved to get a few "legit" jobs at Manhattan first and then when I get my Patriot I go and start my baddass campaign.
I also have a goody goody char but that one is mostly unused now. It gets kinda boring because I only get attacked when I'm venturing outside the patrol routes or when I go cloud-exploring :/