A lot of it depend on you hold size and what you pick up. Atifacts bring the most money, but so do the weps looted from different ships. Some weps can bring 30,000 per wep. There is a spoiler list of wecks and what they have stickyed. You can also mod your hold size to hold more of what ever you want to carry. But rememeber, when you go through hostile areas with a full hold, folks may want it from you.

Think the route your on about is Engine Components from Planet New Berlin to Yanagi Depot in Sigma 13, then Cardamine from Yanagi back to New Berlin

One route that is especially good but that a lot of people seem to ignore is smugling cardamine from the Mactan Base (Magellan System) to Planet Manhattan (NY System). At Mactan you can buy it for 810$ and sell it in NY for 1500$. A profit of 690$ per unit. Plus both systems are just 1 jump gate away. And plenty of trade lanes to speed things up. Bring back H-Fuel from NY.

actually if you want to go by precentage of profits its the 2-200 toxic waste run from the yukon in california or missouri in new york, or any other liberty B-Ship for that matter, to Dortmund station New Berlin. i think its something like a 10000 percent profit, its also one of the cheapest runs, unless you like mining, then i would suggest Omega-41 diamond field to planet Leeds

some fall.... I FLY!

This may be the one you are talking about. I use it and it's quite...rewarding. I got it off the Mercenary Navy Freelancer clan website, thanks guys. This is a direct copy and paste from their site. Just thought i'd point it out to you.

Fly to the Rheinland nation and to the New Berlin system. When you get there, land on planet New Berlin and purchase the Humpback freighter. This shoud set you back around 170,000 credits. Now that you have a great freighter, you need a great route to run it on:

Buy Diamonds At New Berlin>>>>>Sell At Planet New Tokyo>>>>>Sell Niobium At The Ring

This is the most profitable route in the game that has been discovered to date. Although it can be dangerous and diamonds are an attractive targets to the pirates of sigma 13 this will earn you more money than you can spend. (get your corsair rep up in sigma 13 - you'll see why later!)

If you run this route properly you should make around 800,000 credits per journey. Each journey should take no more that 10 - 15 minutes. Keep trading like this until you have the money you need to get yourself a very heavy fighter. Realistically you need around 5-10 million credits if you dont want to trade ever again.

The Mercenary Navy seem pretty smart. Although i've never met one of their members, i owe them a lot of thanks. This set me up to be a made man in multiplayer. Cheers guys!

"Veni, vidi, vici."
(I came, I saw, I conquered)
- Julius Caesar

The Humpback is the worst ship in FL {IMMHWO}. It's name is quite approiate since it flies like a preganant whale on prosac & downers after a 3 day binge of Scotch and Cardamine. It is nearly useless if you get attacked since there is next to no response.
Flying a Bloodhound would be safer.

Fix your rep & get a Dromedary.

Just my opinion.

It is hard to soar with eagles when you fly with turkeys.

I wholeheartedly agree with the New Tokyo -> New Berlin route. I discovered it early on and do it all the time myself, although I try to do it in a Dromedary. Relatively short route, lots of profit, and pretty safe once you're out of Sigma-13.

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Patriot pilot un-extraordinaire.

Speed is my armor, thrusters are my shield.

i cant seem to rmember all the routes, but this tool can help

The Freelancer Cargo Computer

it lists all the routes and hilights the best trade route and best cargo for a given route from one system to another. a gr8 tool.

Try

Buy Boron from Pittsburg for 120
Sell At LD-14 in Leeds, for 980

Valkyrie: Chooser of the Slain

Beryllium from cardiff mining station in Cambridge to The ring, New Berlin.
Stats-
Profit: 1056 credits per units
Profit %: 733%
Distance: 4 jumps
Profit/distance: 264/Jump
Buy price: 144/Unit
Sell price: 1200/Unit

I can EASILY make over 800k in one run in a Dromedary, plus the only pirates you encounter are Outasts in daggers and Stilletos, provided you get yourself some good guns for the trip in omega-3, you shouldnt have any prolems as the Bounty hunters in Omega-7 will have you covered.

All data thanks to Mike Fay's FL_commodities xls file

1. The route below is definitely on the longer side ... and also exposes you to nearly every pirate faction in the sector. If you can make the journey, however, you'll find the price to be well worth it.

Planet New Berlin: Engine Components [225c -> Freital Base [1.050c
Freital Base: Diamonds [198c -> Planet New Tokyo [1.650c
Planet New Tokyo: Luxury Consumer Goods [810c -> Planet Honshu [990c
Planet Honshu: Engine Components [150c -> Arranmore Base [1.500c
Arranmore Base: Gold [271c -> Planet New Berlin [1.189c

Total Profit: 1.340.625c

2. Here's the other route that I picked up on. It's also on the longer side ... and will cost some money to make repairs from radiation damage in Omega-11.

Solarius Station: Diamonds [219c -> Planet New Tokyo [1.650c
Planet New Tokyo: Niobium [512c -> The Ring [1.440c
Planet New Berlin: Mining Machinery [120c -> Solarius Station [499c

Like someone else mentioned in this thread, you can also buy diamonds at New Berlin. If you download the mod for Soulforge's Train (modified by Chips), you'll definitely find the cargo space allows for a sizeable profit in no time at all.

But as a friend of mine once wrote: "But beware of the Corsairs and Outcasts [in Sigma-13, they are merciless and efficient killers ... The interference is high, so don't on seeing the next Ring on your contact list."