IT IS POSSIBLE. Some actions rise your overall rep, some lowers. When Xenos are at -9 blocks to the left (red/hostile) killing them does not change this, but changes other factions, generally in +. Same with others. There is no sense to fly for or bribe the Outcasts, Corsairs and Xenos (in terms of reputation), and there is a sense to do this for police or companies up to 8 blocks to the right as I mentioned erlier. Further actions will make less good or even will lower your overall rep.
And the chain of reputation changes is only 1 level deep,
ie. You kill LSF, LPI goes down but that change (LPI) doesn't make LPI friends to dislike you more. Unless they are LSF friends too

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And I AM friendly with all just playing the game, so don't tell me that I've done imposible things. This is the FACT. If you still not belive in facts, it's your problem.
Tygrys